Thursday, 29 September 2011

Comfora or Elmiron

Elmiron or Comfora:

              Who out there is not worried about their money? Elmiron is burning a big-hole in the pockets of the patients. When you have a chronic illness like IC, money cannot be.
               Comfora is orally bioavailable Pentosan Polysulfate Sodium. Its mechanism of action is thought to be adherence to the bladder surface supplementing the defective natural glycosaminoglycan layer. It is hypothesized that this action ameliorates the symptoms of interstitial cystitis. Orally administered pentosan has a urinary excretion half-life of 4.4 hours for the unchanged drug. A single dose is completely eliminated in 144 hours.
               The recommended dose is 300 mg/day taken as one 100 mg capsule orally 3 times daily. The capsules should be taken with water at least 1 hour before meals or 2 hours after meals
              Some patients with interstitial cystitis may require 6 to 8 weeks of therapy with pentosan to achieve relief of symptoms. Long-term continuation of pentosan therapy is necessary for persistent therapeutic effect.
              Elmiron and Comfora only differ in their price tag. Elmiron placed at a higher value is not affordable by all. Swati Spentose Pvt. Ltd. took the initiative in launching the only Indian Brand- Comfora. large segment of patients, for whom it was difficult to afford Elmiron can now buy it and lead a comforting life even during IC.
             The next issue will cover the All-India USICONS held at the capital as well as the regional USICONS attended by our expert staff.
             The symptoms in women exacerbate just before or during menstruation, during ovulation or if they are taking contraceptive pills. It should be emphasized, however, that many patients never progress further than a relatively mild form of IC.
Refined by Sanaa Jummal

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